Important Safety Information for Sildenafil Users
You may need to decide whether to stop breastfeeding or stop taking this medication. For seniors: The kidneys, liver, or heart of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, a higher amount of a drug stays in your body for a longer time.
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It appears unlikely that this drug will harm a pregnancy. However, this drug should only be used during pregnancy if clearly needed. Viagra or generic sildenafil for ED should not be used in women. For women who are breastfeeding: When used for PAH, sildenafil may pass into breast milk and may cause side effects in a child who is breastfed. Talk with your doctor if you breastfeed your child. This raises your risk for side effects.
- Sildenafil 100g is rarely prescribed and considered an experimental or off-label dose.
- Like all medications, it should only be used as directed by a healthcare professional.
- Overdose signs include severe hypotension, vision loss, or chest pain.
- Use with caution in patients with liver or kidney impairment.
- Avoid alcohol consumption when using sildenafil, especially at high doses.
For children: This drug isn’t recommended in children younger than 18 years. In one study, children with PAH who took this drug had an increased chance for death. All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on: how you react to the first dose Strengths: 25 mg, 50 mg, 100 mg Strengths: 25 mg, 50 mg, 100 mg Typical dosage: 50 mg, taken as needed about 1 hour before sexual activity. It can be taken 30 minutes to 4 hours before sexual activity. Maximum dosage: 100 mg once per day. This drug has not been confirmed to be safe or effective in children younger than 18 years.
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Senior dosage (ages 65 years and older) The kidneys, liver, or heart of older adults may not work as well as they used to. This raises your risk of side effects. Your doctor may start you on a lowered dosage of sildenafil. This can help prevent levels of this drug from building up in your body. Typical dosage: 5 or 20 mg, taken three times per day about 4 to 6 hours apart Maximum dosage: 20 mg, taken three times per day about 4 to 6 hours apart This drug shouldn’t be used in children younger than 18 years of age. Disclaimer: Our goal is to provide you with the most relevant and current information.
| Storage Condition | Details | Temperature Range |
|---|---|---|
| Cool, Dry Place | Keep away from light and moisture | 15-30°C |
| Keep Out of Reach of Children | To prevent accidental ingestion | - |
| Packaging | Original tightly sealed containers | - |
However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. Always speak with your doctor or pharmacist about dosages that are right for you. Sildenafil oral tablet is used for short-term treatment of ED and long-term treatment of PAH. It comes with serious risks if you don’t take it as prescribed. If you stop taking the drug suddenly or don’t take it at all: For ED: Your ED symptoms won’t improve. For PAH: Your condition won’t improve and may get worse. Also, you won’t be able to exercise. If you miss doses or don’t take the drug on schedule: For ED: Your ED symptoms won’t improve. For PAH: This medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.
What happens if I overdose?
Blood pressure drugs, such as amlodipine.Increased side effects can include blood pressure that’s too low. Increased side effects can include blood pressure that’s too low. Other drugs for erectile dysfunction, such as avanafil, tadalafil, or vardenafil.Increased side effects can include low blood pressure or erections that last longer than normal Increased side effects can include low blood pressure or erections that last longer than normal Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice.
Interactions that increase your risk for side effects
Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. Sildenafil can cause a severe allergic reaction. If you develop these symptoms, call 911 or go to the nearest emergency room. Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).
Sildenafil side effects
The use of drinks that contain alcohol raises your risk for low blood pressure from sildenafil. If you drink alcohol, talk with your doctor. You may need to have your blood pressure monitored while you take this drug. For people with heart problems: This drug can lower your blood pressure. If you’ve had certain heart problems in the last 6 months, ask your doctor whether this drug is safe for you. If you take too much: You could have dangerous levels of the drug in your body. Symptoms of an overdose of this drug can include: If you think you’ve taken too much of this drug, call your doctor or local poison control center. If your symptoms are severe, call 911 or go to the nearest emergency room right away.
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Do not take these drugs with sildenafil. Doing so can cause dangerous effects in the body. Nitrates, such as isosorbide mononitrate, isosorbide dinitrate, or nitroglycerin.Taking these drugs with sildenafil can cause your blood pressure to drop suddenly to an unsafe level. Taking these drugs with sildenafil can cause your blood pressure to drop suddenly to an unsafe level. Guanylate cyclase stimulators, such as riociguat.Taking these drugs with sildenafil can cause your blood pressure to drop suddenly to an unsafe level.
What should I do if I accidentally use too much sildenafil?
Side effects from sildenafil: Taking sildenafil with certain medications raises your risk for side effects from sildenafil. This is because the amount of sildenafil in your body is increased. HIV drugs, such as ritonavir, indinavir, saquinavir, or atazanavir.Increased side effects can include low blood pressure, dizziness, or vision problems. They can also include erections that last longer than normal. Increased side effects can include low blood pressure, dizziness, or vision problems.
Drugs you should not use with sildenafil
Certain antibiotics, such as clarithromycin or erythromycin.Increased side effects can include low blood pressure, dizziness, or vision problems. Certain antifungals, such as ketoconazole or itraconazole.Increased side effects can include low blood pressure, dizziness, or vision problems. Side effects from other drugs: Taking sildenafil with certain medications raises your risk for side effects from these drugs. Alpha-blockers, such as terazosin, tamsulosin, doxazosin, alfuzosin, or silodosin.Increased side effects can include a drop in blood pressure, or fainting. Increased side effects can include a drop in blood pressure, or fainting. What to do if you miss a dose: For ED: Take your dose 30 minutes to 4 hours before your next sexual activity. For PAH: Take your dose as soon as you remember. But if you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects. How to tell if the drug is working: For ED: You should be able to get and maintain an erection when sexually aroused. For PAH: You should be able to exercise more easily.
- Sildenafil operates by increasing blood flow to the penis during arousal.
- It is a phosphodiesterase type 5 (PDE5) inhibitor used in sexual medicine.
- The standard dose ranges from 25mg to 100mg, but 100g refers to a very high, rare dose.
- Users should always adhere to prescribed doses to avoid health risks.
- Never attempt to self-medicate with high doses like 100g without professional advice.
Your doctor will also check you to determine if this drug is working. Keep these considerations in mind if your doctor prescribes sildenafil for you. You can take this drug with or without food. You can cut or crush the tablet. When you take the drug depends on the condition being treated:For ED: You can take this drug at any time of day.For PAH: Take this drug three times per day about 4–6 hours apart.
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These problems include a heart attack, stroke, or life threatening heart rhythm problem. Also talk with your doctor if you have a low or high resting blood pressure, or a history of heart failure or coronary artery disease. For people with pulmonary veno-occlusive disease (PVOD): Taking this drug may worsen your heart function. For people with eye problems: This drug may cause sudden loss of vision in one or both eyes. This may be a sign of non-arteritic anterior ischemic optic neuropathy (NAION).
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If you’ve already had NAION or have crowded optic disc, you may have a higher risk for NAION and vision changes with this drug. For people with problems with the shape of their penis: If you have a problem with the shape of your penis, such as Peyronie’s disease, this drug raises your risk for having an erection that lasts more than 4 hours. For people with a history of stomach ulcers or bleeding: This drug raises your risk for stomach bleeding, ulcers, or small holes in the lining of your digestive system. These events can be fatal (cause death). They can happen at any time, with or without symptoms.
What should I tell my healthcare provider before taking sildenafil?
For people with sickle cell anemia: This drug may cause a common painful complication of sickle cell anemia called vaso-occlusive crisis. If you have sickle cell anemia, ask your doctor whether this drug is safe for you. For pregnant women: Research in animals has not shown a risk to the fetus when the mother takes the drug. However, there aren’t enough studies done in humans using the drug for PAH to show if the drug poses a risk to the fetus. Talk with your doctor if sildenafil products over the counter you’re pregnant or planning to become pregnant. Take it at the same time every day.
- Side effects at high doses like 100g can include vision impairment and hearing loss.
- Sildenafil can cause headaches, dizziness, or temporary vision changes.
- Patients taking medications for blood pressure should consult their doctor beforehand.
- The drug's effect lasts around 4-6 hours, but duration varies.
- Misuse or overdose increases the risk of serious health complications.
For ED: You can take this drug at any time of day. For PAH: Take this drug three times per day about 4–6 hours apart. Store sildenafil tablets at room temperature between 59°F and 86°F (15°C and 30°C). Don’t store this medication in moist or damp areas, such as bathrooms. A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription. When flying, never put it into a checked bag. Keep it in your carry-on bag. Don’t worry about airport X-ray machines. You may need to show airport staff the pharmacy label for your medication. Always carry the original prescription-labeled container with you. Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold. If you’re taking this drug for PAH, your doctor may monitor your blood pressure and pulse regularly. When filling your prescription, be sure to call ahead to make sure your pharmacy carries it.
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