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For future questions, you can contact me directly with "A question for Dr. DAGO" via my Just Answer direct link provided below; Disclaimer: The customer and expert messages presented herein may have been altered or modified to enhance readability and safeguard the privacy of individuals. These modifications do not change the intent or substance of the original messages.
Who is Viagra suitable for?
Remember to check back in a few days to let me know how you're feeling! I’m here to ensure you fully comprehend the information I’ve shared. Please buy female viagra feel free to ask any further questions or express your concerns—I’m dedicated to assisting you through this complex situation. If you have additional inquiries later, you can easily locate me on your "My Questions" page by rating our interaction. Take care of yourself, and prioritize your health and safety. VIAGRA- sildenafil citrate tablet, film coated Rebel Distributors Corp VIAGRA®, an oral therapy for erectile dysfunction, is the citrate salt of sildenafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Sildenafil citrate is designated chemically as 1-[[3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1 ]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate and has the following structural formula: Sildenafil citrate is a white to off-white crystalline powder with a solubility of 3.5 mg/mL in water and a molecular weight of 666.7. VIAGRA (sildenafil citrate) is formulated as blue, film-coated rounded-diamond-shaped tablets equivalent to 25 mg, 50 mg and 100 mg of sildenafil for oral administration. The physiologic mechanism of erection of the penis involves release of nitric oxide (NO) in the corpus cavernosum during sexual stimulation.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Viagra Generic | 25mg | 360 + 10 Pills | 213.68€ 203.50€ | |
| Viagra Generic | 50mg | 10 Pills | 26.87€ 25.59€ | |
| Viagra Super Active | 100mg | 30 + 6 Pills | 64.09€ 61.04€ | |
| Viagra Super Active | 100mg | 10 Pills | 28.76€ 27.39€ | |
| Viagra Super Active | 100mg | 90 + 10 Pills | 165.61€ 157.72€ | |
| Viagra Original | 100mg | 120 + 8 Pills | 470.39€ 447.99€ | |
| Viagra Generic | 200mg | 270 + 10 Pills | 379.76€ 361.68€ | |
| Viagra Oral Jelly | 100mg | 21 Sachets | 78.66€ 74.91€ | |
| Viagra Generic | 150mg | 360 + 10 Pills | 423.48€ 403.31€ | |
| Viagra Generic | 50mg | 270 + 8 Pills | 198.48€ 189.03€ | |
| Viagra Original | 100mg | 48 + 4 Pills | 207.15€ 197.29€ | |
| Viagra Generic | 150mg | 20 Pills | 55.02€ 52.40€ | |
| Viagra Original | 100mg | 22 + 2 Pills | 120.71€ 114.96€ | |
| Viagra Generic | 100mg | 60 + 4 Pills | 96.36€ 91.77€ | |
| Viagra Generic | 25mg | 30 + 4 Pills | 47.97€ 45.69€ | |
| Viagra Oral Jelly | 100mg | 63 + 7 Sachets | 190.54€ 181.47€ |
NO then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood.
Medical uses
Doctor's Assistant: Thank you for that information. Lastly, could you let me know if your doctor provided any specific instructions or advice regarding the use of Viagra? This will help the Expert tailor their guidance. Hello, I am a physician in the USA with over 15 years of experience. I will dedicate my time to provide you with excellent service and support.
Can women take Viagra?
I am eager to learn about your situation and assist you in any way possible. Please feel free to share any details or concerns with me. May I inquire about your age, as this information can assist in evaluating your risk for side effects? Have you ever encountered any vision changes or eye issues in the past, even if they were not related to medication? However, several years ago, I was considered a glaucoma suspect, but I was cleared after undergoing tests. Sildenafil has no direct relaxant effect on isolated human corpus cavernosum, but enhances the effect of nitric oxide (NO) by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum. When sexual stimulation causes local release of NO, inhibition of PDE5 by sildenafil causes increased levels of cGMP in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Sildenafil at recommended doses has no effect in the absence of sexual stimulation.
Peds Dosing .
Doctor's Assistant: I understand you're feeling cautious about taking Viagra for the first time and are considering starting with a lower dose. To help the Expert provide the best guidance, could you share if you have any pre-existing medical conditions, such as heart issues or high blood pressure? Customer: No, I do not have either. Doctor's Assistant: Thank you for letting me know. Have you experienced any side effects or sensitivities to medications in the past?
Drug form and strengths
This will help the Expert understand your situation better. Doctor's Assistant: Got it, thank you for sharing that. Could you let me know if you're currently taking any other medications or supplements? This can help the Expert assess potential interactions. Customer: I'm taking multivitamins, B-complex, viagra vardenafil 20mg and Zyrtec as needed. Studies in vitro have shown that sildenafil is selective for PDE5. Its effect is more potent on PDE5 than on other known phosphodiesterases (10-fold for PDE6, >80-fold for PDE1, >700-fold for PDE2, PDE3, PDE4, PDE7, PDE8, PDE9, PDE10, and PDE11). The approximately 4,000-fold selectivity for PDE5 versus PDE3 is important because PDE3 is involved in control of cardiac contractility. Sildenafil is only about 10-fold as potent for PDE5 compared to PDE6, an enzyme found in the retina which is involved in the phototransduction pathway of the retina.
| Condition or Medication | Why It Matters | Alternatives |
|---|---|---|
| Nitrate medication | Can cause dangerous hypotension | Use other ED treatments |
| Severe heart disease | Increased risk of cardiovascular events | Non-pharmacological methods |
| Liver impairment | Altered drug metabolism | Lower doses or different medications |
This lower selectivity is thought to be the basis for abnormalities related to color vision observed with higher doses or plasma levels (see Pharmacodynamics ).
Shipping Information
This medicine is not intended for use by women and men should avoid using any other medicines to treat impotence without talking to a doctor first. Avoid drinking alcohol while taking this medicine as it increases the chances of side effects. In Erectile dysfunctionViagra 25mg Tablet belongs to a group of medicines called PDE5 inhibitors. It is very effective but needs to be taken at least 30 minutes before sexual activity.Do not take this medicine if you also take medicines called nitrates (often given for chest pain). Side Effects of Viagra TabletMost side effects do not require any medical attention and disappear as your body adjusts to the medicine.
How to get Viagra
Consult your doctor if they persist or if you’re worried about them Flushing (sense of warmth in the face, ears, neck and trunk) How To Use Viagra TabletTake This Medicine In The Dose And Duration As Advised By Your Doctor. Viagra 25mg Tablet May Be Taken With Or Without Food, But It Is Better To Take It At A Fixed Time. Exports To: United States Of America Germany Czech Republic The Netherlands Brazil VIAGRA 100 MG (PFIZER) 1X1 Nagpur, MaharashtraAsk Price 50mg Viagra Sildenafil Tablets Nagpur, Maharashtra₹ 258/Box Sildenafil Tablets 100 mg Nagpur, Maharashtra₹ 500/Strip Viagra 100 Mg Tablet (10 Tablets) Nagpur, Maharashtra₹ 100/Box 100MG VIAGRA TABLETS Nagpur, Maharashtra₹ 2,000/Box 100mg Viagra Sildenafil Tablets Nagpur, Maharashtra₹ 1,200/Strip United States Of America Germany Czech Republic The Netherlands Brazil I have a 50 mg prescription, but I'm having second thoughts about using it due to potential side effects. I was considering cutting it in half and trying 25 mg. Should I be worried? In addition to human corpus cavernosum smooth muscle, PDE5 is also found in lower concentrations in other tissues including platelets, vascular and visceral smooth muscle, and skeletal muscle. The inhibition of PDE5 in these tissues by sildenafil may be the basis for the enhanced platelet antiaggregatory activity of nitric oxide observed in vitro, an inhibition of platelet thrombus formation in vivo and peripheral arterial-venous dilatation in vivo.
Why has Viagra been approved?
Just after my orthopedic surgery, I experienced an upset stomach. Considering your age and previous concerns regarding glaucoma, it's prudent to exercise caution. Nevertheless, your current health condition does not indicate significant risk factors. Initiating treatment with a lower dose, such as 25 mg, is a sensible strategy to reduce the likelihood of potential side effects. Is there anything you would like to clarify or discuss in more detail? VIAGRA is rapidly absorbed after oral administration, with a mean absolute bioavailability of 41% (range 25–63%). Its pharmacokinetics are dose-proportional over the recommended dose range.
- The 25 mg tablet is a precise dose manufactured under strict quality controls.
- PDE5 is found in other tissues, explaining side effects like nasal congestion.
- It can be prescribed for off-label uses under a doctor's careful supervision.
- Men with unstable angina or uncontrolled arrhythmias should not use.
- The medication can be detected in urine drug tests designed for sildenafil.
- It is not a steroid and does not build muscle.
- Can improve erectile function in men with ED due to multiple sclerosis.
- The placebo effect in ED treatment trials is often significant.
- A vacuum constriction device is a non-pharmacological alternative.
- The goal of treatment is satisfactory sexual intercourse for the patient/partner.
- Disposal via drug take-back programs is preferred over flushing or trash.
It is eliminated predominantly by hepatic metabolism (mainly cytochrome P450 3A4) and is converted to an active metabolite with properties similar to the parent, sildenafil. Both sildenafil and the metabolite have terminal half lives of about 4 hours. Mean sildenafil plasma concentrations measured after the administration of a single oral dose of 100 mg to healthy male volunteers is depicted below: Maximum observed plasma concentrations are reached within 30 to 120 minutes (median 60 minutes) of oral dosing in the fasted state. When VIAGRA is taken with a high fat meal, the rate of absorption is reduced, with a mean delay in Tmax of 60 minutes and a mean reduction in Cmax of 29%. The mean steady state volume of distribution (Vss) for sildenafil is 105 L, indicating distribution into the tissues.
- The safety profile of 25 mg Viagra is well-studied with low incidence of serious side effects.
- Patients should schedule follow-up appointments to monitor response.
- It is important to consider interactions with medications like antihypertensives.
- Take note of any allergic reactions such as rash or swelling.
- Some men may achieve optimal results by adjusting the dose under supervision.
- Do not share Viagra with others, as it can cause adverse effects in certain individuals.
- Combining Viagra with nitrates can cause dangerous drops in blood pressure.
Sildenafil and its major circulating N-desmethyl metabolite are both approximately 96% bound to plasma proteins.
Route of administration
This medicine will only help get an erection if you are sexually stimulated. It is very effective but needs to be taken at least 30 minutes before sexual activity.Do not take this medicine if you also take medicines called nitrates (often given for chest pain).Side Effects of Viagra TabletMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of ViagraHow To Use Viagra TabletTake This Medicine In The Dose And Duration As Advised By Your Doctor. Viagra 25mg Tablet May Be Taken With Or Without Food, But It Is Better To Take It At A Fixed Time.How Viagra Tablet WorksViagra 25mg Tablet Is A Phosphodiesterase-5 (Pde-5) Inhibitor. It Works By Relaxing The Blood Vessels In Your Penis, Thereby Increasing Blood Flow Into The Penis On Sexual Stimulation.
Generic Name
This Helps You Achieve And Maintain A Hard, Erect Penis Suitable For Sexual Activity. Viagra 25mg Tablet may be taken on an empty stomach or with a meal. It should not be taken more than once a day. The most common side effects of this medicine are flushing (sense of warmth), headache, dizziness, blurred vision, muscle pain, stomach upset, and rash. Talk to your doctor if any of the side effects bother you or do not go away. Protein binding is independent of total drug concentrations. Based upon measurements of sildenafil in semen of healthy volunteers 90 minutes after dosing, less than 0.001% of the administered dose may appear in the semen of patients.